JMIRx Medxmed34JMIRx MedJMIRx Med2563-6316JMIR PublicationsToronto, Canadav6i1e7952110.2196/79521Peer-Review ReportPeer Review of “Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort Study”AdhikariArchanaSikkim Manipal UniversityGangtokIndiaWuFuqing202531720256e795212306202523062025© Archana Adhikari. Originally published in JMIRx Med (https://med.jmirx.org), 31.7.2025. 2025

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Med, is properly cited. The complete bibliographic information, a link to the original publication on https://med.jmirx.org/, as well as this copyright and license information must be included.

https://www.medrxiv.org/content/10.1101/2024.08.10.24311795v1https://med.jmirx.org/2025/1/e79672https://med.jmirx.org/2025/1/e65299cardiotoxicitycardiologycardiovascularheartarrhythmiasself-reported questionnairesoncologysurvivorspediatricsprevalenceincidenceriskepidemiologyanthracycline exposurechildhood cancer survivors

This is a peer-review report for “Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort Study.”

Round 1 ReviewGeneral Comments

This paper [1] gives valuable insights into cardiotoxicity in pediatric cancer survivorship: patterns, predictors, and implications for long-term care. The results and methodology are sound. However, some minor revisions would improve clarity and strengthen the overall impact of this paper. Below are my suggestions.

Major Comments

Method section (study population and data source): In the Method section, specifically the fourth line, the description “of 21 at one of 31 participating institutes” is unclear. The sentence should be revised for better clarity.

Missing answer for seventh objective: The answer to the seventh objective is unclear.

Minor Comments

Result presentation: It would be better if the results were presented in tabular format for easier comprehension. A table would help summarize the key findings and increase readability.

Clarity in results numbering: To improve clarity, it would be beneficial to present all the results with corresponding numbers, matching each result with the respective objective number for easier reference and alignment.

None declared.

ReferencesMansoorM IbrahimA Cardiotoxicity in Pediatric Cancer Survivorship: Retrospective Cohort StudyJMIRx Med20256e6529910.2196/65299