<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="reviewer-report"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIRx Med</journal-id><journal-id journal-id-type="publisher-id">xmed</journal-id><journal-id journal-id-type="index">34</journal-id><journal-title>JMIRx Med</journal-title><abbrev-journal-title>JMIRx Med</abbrev-journal-title><issn pub-type="epub">2563-6316</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v6i1e69705</article-id><article-id pub-id-type="doi">10.2196/69705</article-id><article-categories><subj-group subj-group-type="heading"><subject>Peer-Review Report</subject></subj-group></article-categories><title-group><article-title>Peer Review for &#x201C;Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review&#x201D;</article-title></title-group><contrib-group><contrib contrib-type="author"><collab>Anonymous</collab></contrib></contrib-group><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Tungjitviboonkun</surname><given-names>Songphol</given-names></name></contrib></contrib-group><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>6</day><month>1</month><year>2025</year></pub-date><volume>6</volume><elocation-id>e69705</elocation-id><history><date date-type="received"><day>05</day><month>12</month><year>2024</year></date><date date-type="accepted"><day>05</day><month>12</month><year>2024</year></date></history><copyright-statement>&#x00A9; Anonymous. Originally published in JMIRx Med (<ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org">https://med.jmirx.org</ext-link>), 6.1.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Med, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org/">https://med.jmirx.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://xmed.jmir.org/2025/1/e69705"/><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.1101/2024.07.30.24311256" xlink:title="Preprint (medRxiv)" xlink:type="simple">https://www.medrxiv.org/content/10.1101/2024.07.30.24311256v1</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/68769" xlink:title="Authors' Response to Peer-Review Reports" xlink:type="simple">https://med.jmirx.org/2025/1/e68769</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/66213" xlink:title="Published Article" xlink:type="simple">https://med.jmirx.org/2025/1/e66213</related-article><kwd-group><kwd>indocyanine green</kwd><kwd>ICG</kwd><kwd>sentinel lymph node</kwd><kwd>breast cancer</kwd><kwd>breast</kwd><kwd>fluorescence</kwd><kwd>axillary lymph node mapping</kwd><kwd>NIR</kwd><kwd>surgical planning</kwd><kwd>near-infrared</kwd></kwd-group></article-meta></front><body><p><italic>This is the peer-review report for &#x201C;Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review.&#x201D;</italic></p><sec id="s2"><title>Round 1 Review</title><sec id="s1-1"><title>General Comments</title><p>This paper [<xref ref-type="bibr" rid="ref1">1</xref>] summarized the application value and existing problems of indocyanine green (ICG) in sentinel lymph node (SLN) biopsy of early breast cancer, which has positive significance for improving the accuracy of clinical SLN detection. This study has certain clinical value.</p></sec><sec id="s1-2"><title>Specific Comments</title><sec id="s1-2-1"><title>Major Comments</title><list list-type="order"><list-item><p>Due to the high hardware requirements for the clinical application of ICG, the number of relevant studies in the search is relatively small. It is hoped that the author can search the recent relevant literature to improve the credibility of this review.</p></list-item><list-item><p>It is hoped that the author will analyze and compare the advantages and disadvantages of ICG and traditional SLN biopsy methods, so as to guide clinicians to adopt appropriate methods for appropriate patients.</p></list-item></list></sec></sec></sec></body><back><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">ICG</term><def><p>indocyanine green</p></def></def-item><def-item><term id="abb2">SLN</term><def><p>sentinel lymph node</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Kurdi</surname><given-names>F</given-names> </name><name name-style="western"><surname>Kurdi</surname><given-names>Y</given-names> </name><name name-style="western"><surname>Reshetov</surname><given-names>IV</given-names> </name></person-group><article-title>Applications of indocyanine green in breast cancer for sentinel lymph node mapping: protocol for a scoping review</article-title><source>JMIRx Med</source><year>2024</year><volume>5</volume><fpage>e66213</fpage><pub-id pub-id-type="doi">10.2196/66213</pub-id></nlm-citation></ref></ref-list></back></article>