<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="reviewer-report"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIRx Med</journal-id><journal-id journal-id-type="publisher-id">xmed</journal-id><journal-id journal-id-type="index">34</journal-id><journal-title>JMIRx Med</journal-title><abbrev-journal-title>JMIRx Med</abbrev-journal-title><issn pub-type="epub">2563-6316</issn></journal-meta><article-meta><article-id pub-id-type="publisher-id">60329</article-id><article-id pub-id-type="doi">10.2196/60329</article-id><title-group><article-title>Peer Review of &#x201C;Dental Tissue Density in Healthy Children Based on Radiological Data: Retrospective Analysis&#x201D;</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Gorthy</surname><given-names>Shanmukha</given-names></name><degrees>BDS, MDS</degrees><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Drs Sudha &#x0026; Nageswara Rao Siddhartha Institute of Dental Sciences</institution>, <addr-line>Chinoutpalli</addr-line>, <country>India</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Meinert</surname><given-names>Edward</given-names></name></contrib></contrib-group><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>20</day><month>6</month><year>2024</year></pub-date><volume>5</volume><elocation-id>e60329</elocation-id><history><date date-type="received"><day>07</day><month>05</month><year>2024</year></date><date date-type="accepted"><day>07</day><month>05</month><year>2024</year></date></history><copyright-statement>&#x00A9; Shanmukha Gorthy. Originally published in JMIRx Med (<ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org">https://med.jmirx.org</ext-link>), 20.6.2024. </copyright-statement><copyright-year>2024</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Med, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org/">https://med.jmirx.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://xmed.jmir.org/2024/1/e60329"/><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/preprints.56759" xlink:title="Preprint (JMIR Preprints)" xlink:type="simple">https://preprints.jmir.org/preprint/56759</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.1101/2024.01.11.24301001" xlink:title="Preprint (medrxiv)" xlink:type="simple">https://www.medrxiv.org/content/10.1101/2024.01.11.24301001v1</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/56759" xlink:title="Published Article" xlink:type="simple">https://med.jmirx.org/2024/1/e56759</related-article><kwd-group><kwd>density</kwd><kwd>teeth</kwd><kwd>tooth</kwd><kwd>dental</kwd><kwd>dentist</kwd><kwd>dentists</kwd><kwd>dentistry</kwd><kwd>oral</kwd><kwd>tissue</kwd><kwd>enamel</kwd><kwd>dentin</kwd><kwd>Hounsfield</kwd><kwd>pathology</kwd><kwd>pathological</kwd><kwd>radiology</kwd><kwd>radiological</kwd><kwd>image</kwd><kwd>images</kwd><kwd>imaging</kwd><kwd>teeth density</kwd><kwd>Hounsfield unit</kwd><kwd>diagnostic imaging</kwd></kwd-group></article-meta></front><body><p><italic>This is the peer-review report for</italic> &#x201C;<italic>Dental Tissue Density in Healthy Children Based on Radiological Data: Retrospective Analysis.&#x201D;</italic></p><sec id="s2"><title>Round 1 Review</title><sec id="s1-1"><title>General Comments</title><p>This paper [<xref ref-type="bibr" rid="ref1">1</xref>] has a very good topic selected by the authors. Based on the study of Hounsfield units in cone-beam computed tomography (CBCT), we can evaluate conditions that are abnormal in patients.</p></sec><sec id="s1-2"><title>Specific Comments</title><p>There is not much to comment on, but try to include good pictures of the CBCT.</p><sec id="s1-2-1"><title>Major Comments</title><p>1. The authors did not mention the ideal values of the Hounsfield units for enamel and dentin.</p><p>2. The authors did not properly explained why there were no gender differences.</p><p>3. The authors did not explain why there were the fewest density values for second primary molars and the most density values for maxillary central incisors.</p></sec></sec></sec></body><back><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">CBCT</term><def><p>cone-beam computed tomography</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Reshetnikov</surname><given-names>A</given-names> </name><name name-style="western"><surname>Shaikhattarova</surname><given-names>N</given-names> </name><name name-style="western"><surname>Mazurok</surname><given-names>M</given-names> </name><name name-style="western"><surname>Kasatkina</surname><given-names>N</given-names> </name></person-group><article-title>Dental tissue density in healthy children based on radiological data: retrospective analysis</article-title><source>JMIRx Med</source><year>2024</year><volume>5</volume><fpage>e56759</fpage><pub-id pub-id-type="doi">10.2196/56759</pub-id></nlm-citation></ref></ref-list></back></article>