<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="reviewer-report"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIRx Med</journal-id><journal-id journal-id-type="publisher-id">xmed</journal-id><journal-id journal-id-type="index">34</journal-id><journal-title>JMIRx Med</journal-title><abbrev-journal-title>JMIRx Med</abbrev-journal-title><issn pub-type="epub">2563-6316</issn></journal-meta><article-meta><article-id pub-id-type="publisher-id">58320</article-id><article-id pub-id-type="doi">10.2196/58320</article-id><title-group><article-title>Peer Review of &#x201C;Detecting Substance Use Disorder Using Social Media Data and the Dark Web: Time- and Knowledge-Aware Study&#x201D;</article-title></title-group><contrib-group><contrib contrib-type="author"><collab>Anonymous</collab></contrib></contrib-group><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Meinert</surname><given-names>Edward</given-names></name></contrib></contrib-group><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>1</day><month>5</month><year>2024</year></pub-date><volume>5</volume><elocation-id>e58320</elocation-id><history><date date-type="received"><day>12</day><month>03</month><year>2024</year></date><date date-type="accepted"><day>12</day><month>03</month><year>2024</year></date></history><copyright-statement>&#x00A9; Anonymous. Originally published in JMIRx Med (<ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org">https://med.jmirx.org</ext-link>), 1.5.2024. </copyright-statement><copyright-year>2024</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Med, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://med.jmirx.org/">https://med.jmirx.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://xmed.jmir.org/2024/1/e58320"/><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/preprints.10512" xlink:title="Preprint (arXiv)" xlink:type="simple">https://arxiv.org/abs/2304.10512</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/57838" xlink:title="Authors&#x2019; Response to Peer-Review Reports" xlink:type="simple">https://med.jmirx.org/2024/1/e57838</related-article><related-article related-article-type="companion" ext-link-type="doi" xlink:href="10.2196/48519" xlink:title="Published Article" xlink:type="simple">https://med.jmirx.org/2024/1/e48519</related-article><kwd-group><kwd>opioid</kwd><kwd>substance use</kwd><kwd>substance use disorder</kwd><kwd>social media</kwd><kwd>US</kwd><kwd>opioid crisis</kwd><kwd>mental health</kwd><kwd>substance misuse</kwd><kwd>crypto</kwd><kwd>dark web</kwd><kwd>users</kwd><kwd>user perception</kwd><kwd>fentanyl</kwd><kwd>synthetic opioids</kwd><kwd>United States</kwd></kwd-group></article-meta></front><body><p><italic>This is the peer-review report for &#x201C;Detecting Substance Use Disorder Using Social Media Data and the Dark Web: Time- and Knowledge-Aware Study.&#x201D;</italic></p><sec id="s2"><title>Round 1 Review</title><p>This study [<xref ref-type="bibr" rid="ref1">1</xref>] can be considered for publication if the researchers are able to revise it to improve the clarity of the objective, theoretical relevance, and practical value. I will suggest that there should be a segment on the objective of the study immediately after the introduction. This will help in giving the study a direction. Please, include this citation:</p><p>Obosi AC, Fatunbi AM, Oyinloye O. Peer pressure and substance use as predictors of mental health among in-school adolescents in Nigeria. <italic>Ianna J Interdisciplinary Stud</italic>. 2022;4(1):1&#x2010;9.</p><p>Explain the implication of your findings to other countries, that is, give the study an international outlook.</p></sec></body><back><fn-group><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="journal"><person-group person-group-type="author"><name name-style="western"><surname>Lokala</surname><given-names>U</given-names></name><name name-style="western"><surname>Phukan</surname><given-names>OC</given-names></name><name name-style="western"><surname>Dastidar</surname><given-names>TG</given-names></name><name name-style="western"><surname>Lamy</surname><given-names>F</given-names></name><name name-style="western"><surname>Daniulaityte</surname><given-names>R</given-names></name><name name-style="western"><surname>Sheth</surname><given-names>A</given-names></name></person-group><article-title>Detecting substance use disorder using social media data and the dark web: time- and knowledge-aware study</article-title><source>JMIRx Med</source><year>2024</year><volume>5</volume><fpage>e48519</fpage><pub-id pub-id-type="doi">10.2196/48519</pub-id></nlm-citation></ref></ref-list></back></article>