JMIRxMed JMIRx Med JMIRx Med 2563-6316 JMIR Publications Toronto, Canada v3i2e38420 10.2196/38420 Peer-Review Report Peer-Review Report Peer Review of “Modeling Years of Life Lost Due to COVID-19, Socioeconomic Status, and Nonpharmaceutical Interventions: Development of a Prediction Model” Meinert Edward Anonymous Apr-Jun 2022 12 4 2022 3 2 e38420 31 3 2022 31 3 2022 © Anonymous. Originally published in JMIRx Med (https://med.jmirx.org), 12.04.2022. 2022

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 https://www.medrxiv.org/content/10.1101/2021.04.23.21256005v1 https://preprints.jmir.org/preprint/30144 https://med.jmirx.org/2022/2/e38008/ https://med.jmirx.org/2022/2/e30144/ COVID-19 pandemic socioeconomic status mortality nonpharmaceutical interventions prediction model low-income status life expectancy public health income groups

This is a peer-review report submitted for the paper “Modeling Years of Life Lost Due to COVID-19, Socioeconomic Status, and Nonpharmaceutical Interventions: Development of a Prediction Model.”

Review Round 1

This paper [1] develops a model that compares the years of life lost (YLL) due to COVID-19 and the potential YLL due to the socioeconomic consequences of its containment. The results highlight the importance of socioeconomic status (SES) in evaluating the effect of nonpharmaceutical interventions (NPIs) during COVID-19. However, the methods, especially the empirical sample characteristics from which the life table is derived, are not clear.

Specific Comments Major Comments

1. Needs to describe more about the data, study design, and study sample in more detail

2. Needs to discuss how the missing data was handled

3. It is important to consider a theoretical framework that can guide the selection of NPIs, indicators of SES, and the equivalent socioeconomic damages (on page 11). Right now, it is more arbitrary than scientific based.

4. The Discussion also needs to consider other factors (eg, pre-existing conditions, neighborhood resources, or occupation types). These are important social determinants of health factors

 Minor Comments

1. The tables need to be adjusted in terms of the decimal points and more informative legends to guide readers.

 Abbreviations NPI

nonpharmaceutical intervention

 SES

socioeconomic status

 YLL

years of life lost

None declared.

 John J Modeling years of life lost due to COVID-19, socioeconomic status, and nonpharmaceutical interventions: development of a prediction model JMIRx Med 2022 3 2 e30144