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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMIRxMed</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIRx Med</journal-id>
      <journal-title>JMIRx Med</journal-title>
      <issn pub-type="epub">2563-6316</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v2i3e33496</article-id>
      <article-id pub-id-type="pmid">27629825</article-id>
      <article-id pub-id-type="doi">10.2196/33496</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Authors' Response to Peer Reviews</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Authors' Response to Peer Reviews</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Authors' Response to Peer Reviews of “Early Experience With Neutralizing Monoclonal Antibody Therapy for COVID-19: Retrospective Cohort Survival Analysis and Descriptive Study”</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Meinert</surname>
            <given-names>Edward</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Jarrett</surname>
            <given-names>Mark</given-names>
          </name>
          <degrees>MBA, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Donald and Barbara Zucker School of Medicine at Hofstra/Northwell</institution>
            <institution>Hofstra University</institution>
            <addr-line>500 Hofstra University</addr-line>
            <addr-line>Hempstead, NY, 11549</addr-line>
            <country>United States</country>
            <phone>1 516 463 7516</phone>
            <email>mjarrett@northwell.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9252-3471</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Licht</surname>
            <given-names>Warren</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-8857-0814</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Bock</surname>
            <given-names>Kevin</given-names>
          </name>
          <degrees>MHCDS, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8320-7482</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Brown</surname>
            <given-names>Zenobia</given-names>
          </name>
          <degrees>MPH, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4514-4839</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Hirsch</surname>
            <given-names>Jamie</given-names>
          </name>
          <degrees>MA, MSB, MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9571-1275</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Coppa</surname>
            <given-names>Kevin</given-names>
          </name>
          <degrees>BSc</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9059-1235</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Brar</surname>
            <given-names>Rajdeep</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-0721-8179</ext-link>
        </contrib>
        <contrib id="contrib8" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Bello</surname>
            <given-names>Stephen</given-names>
          </name>
          <degrees>PA, MHCDS</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3692-3734</ext-link>
        </contrib>
        <contrib id="contrib9" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Nash</surname>
            <given-names>Ira</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3979-8166</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Donald and Barbara Zucker School of Medicine at Hofstra/Northwell</institution>
        <institution>Hofstra University</institution>
        <addr-line>Hempstead, NY</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Northwell Health</institution>
        <addr-line>New Hyde Park, NY</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Mark Jarrett <email>mjarrett@northwell.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Jul-Sep</season>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>27</day>
        <month>9</month>
        <year>2021</year>
      </pub-date>
      <volume>2</volume>
      <issue>3</issue>
      <elocation-id>e33496</elocation-id>
      <history>
        <date date-type="received">
          <day>9</day>
          <month>9</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>9</day>
          <month>9</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Mark Jarrett, Warren Licht, Kevin Bock, Zenobia Brown, Jamie Hirsch, Kevin Coppa, Rajdeep Brar, Stephen Bello, Ira Nash. Originally published in JMIRx Med (https://med.jmirx.org), 27.09.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIRx Med, is properly cited. The complete bibliographic information, a link to the original publication on https://med.jmirx.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://med.jmirx.org/2021/3/e33496" xlink:type="simple"/>
      <related-article related-article-type="companion" id="preprint21255219" ext-link-type="doi" xlink:href="10.1101/2021.04.09.21255219" vol="1" page="21255219" xlink:title="Preprint (medRxiv):" xlink:type="simple">https://www.medrxiv.org/content/10.1101/2021.04.09.21255219v1</related-article>
      <related-article related-article-type="companion" id="preprint29638" ext-link-type="doi" xlink:href="https://doi.org/10.2196/preprints.29638" vol="2" page="e29638" xlink:title="Preprint (JMIR Preprints):" xlink:type="simple">https://preprints.jmir.org/preprint/29638</related-article>
      <related-article related-article-type="companion" id="v2i3e33499" ext-link-type="doi" xlink:href="10.2196/33499" vol="2" page="e33499" xlink:title="Peer-Review Report by Anonymous:" xlink:type="simple">https://med.jmirx.org/2021/3/e33499/</related-article>
      <related-article related-article-type="companion" id="v2i3e29638" ext-link-type="doi" xlink:href="10.2196/29638" vol="2" page="e29638" xlink:title="Published Article:" xlink:type="simple">https://med.jmirx.org/2021/3/e29638/</related-article>
      <kwd-group>
        <kwd>infectious disease</kwd>
        <kwd>monoclonal antibody therapy</kwd>
        <kwd>COVID-19</kwd>
        <kwd>experience</kwd>
        <kwd>therapy</kwd>
        <kwd>drug</kwd>
        <kwd>patient outcome</kwd>
        <kwd>risk</kwd>
        <kwd>efficacy</kwd>
        <kwd>approach</kwd>
        <kwd>treatment</kwd>
        <kwd>pandemic</kwd>
        <kwd>antibody</kwd>
        <kwd>immunotherapy</kwd>
        <kwd>immune therapy</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <p>
      <italic>This is the authors’ response to peer-review reports for “Early Experience With Neutralizing Monoclonal Antibody Therapy for COVID-19: Retrospective Cohort Survival Analysis and Descriptive Study.”</italic>
    </p>
    <sec>
      <title>Round 1 Review [<xref ref-type="bibr" rid="ref1">1</xref>]</title>
      <list list-type="order">
        <list-item>
          <p>Formatting in paper [<xref ref-type="bibr" rid="ref2">2</xref>] changed as requested</p>
        </list-item>
        <list-item>
          <p>Figures changed</p>
        </list-item>
        <list-item>
          <p>Added suggested contextualization</p>
        </list-item>
        <list-item>
          <p>Fortified Discussion</p>
        </list-item>
        <list-item>
          <p>Although we added references and discussion of the inflammatory response to cytokines, it should be recognized that these antibodies work by neutralization of the virus, not by affecting cytokines.</p>
        </list-item>
      </list>
    </sec>
  </body>
  <back>
    <app-group/>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
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          <source>JMIRx Med</source>
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  </back>
</article>
